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PF-3758309 hydrochloride Size:Contact [email protected] for quotation InChi: InChI=1S/C8H7N3O2

SKU: 10162391397

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Description

InChi: InChI=1S/C8H7N3O2

Concomitant treatment with Y-320 and anti-mouse TNF-alpha antibody showed a synergistic effect in mouse CIA

Xuan Zhang

9R)-7-(acetyloxy)-8-hydrogenio-4

PF-3758309 hydrochloride Size:Contact [email protected] for quotation InChi: InChI=1S/C8H7N3O2PF 3758309 hydrochloride is a potent, orally available, and reversible ATP competitive inhibitor of PAK4 (Kd= 2. 7 nM; Ki=18. 7 nM). PF 3758309 hydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation. Product information CAS Number: 1279034 84 2 Molecular Weight: 527. 08 Formula: C25H31ClN8OS Chemical Name: (S) N

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